The science behind TPE.
We believe in full transparency and rigorous science. Here’s a curated selection of studies and insights on Therapeutic Plasma Exchange.
Dr. Michael Roizen
CEO & Co-founder
Dr. Dobri Kiprov
Chief Medical Officer
Patrick Cox
Chief Research Officer
Latest Research
Aging & Vitality
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How Plasma Exchange Could Help Turn Back the Clock on Aging
By Dr. Dobri Kiprov Chief Medical Officer A recent study explored how a procedure called therapeutic plasma exchange (TPE) could slow down the biological aging process. TPE involves removing a person’s blood plasma and replacing it with a plasma substitute, sometimes combined with immunoglobulins (IVIG). The study showed that this procedure not only helps “reset”…
Brain Health
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AMBAR (Alzheimer Management by Albumin Replacement) Study
The AMBAR (Alzheimer Management by Albumin Replacement) study explored a unique treatment approach that involves removing and replacing a portion of a person’s blood plasma—known as plasma exchange—to see if it might help slow the progression of Alzheimer’s disease. Researchers tested this procedure in people with mild-to-moderate Alzheimer’s, aiming to filter out and replace specific…
Dr. Michael Roizen
on the future of aging
Why TPE matters now, and where longevity medicine is headed.
Insights from
Dr. Dobri Kiprov
Why he’s advocated for this therapy for decades, and what he’s seeing in real clients today.
For the clinically curious.
For those who want to go deeper, here’s a curated archive of peer-reviewed studies, review articles, and conference abstracts related to plasma exchange and aging.
Disclaimer: These articles are shared for educational purposes and may contain complex or preliminary findings not yet approved for treatment guidance.
It’s personal.
To truly understand TPE’s potential, we want to start with a personal story. In this video, our founders Dr. Michael Roizen and John Mauldin discuss John’s transformative experience with TPE. Hear how Dr. Roizen, as John’s personal physician, helped guide him to this breakthrough therapy.
Curious about what TPE could do for you?
Schedule a no-pressure call with our team to learn more.