Research Therapeutic Plasma Exchange June 11, 2025 / June 13, 2025 by Jonathan Vandeput Therapeutic Plasma Exchange as a Tool for Reversing Age-Related System Dysfunction With A Special Emphasis On Reversing Brain Dysfunction By Patrick Cox, Research Analyst, Lifespan Edge, Inc. Brief Foreword By Dr. Michael Roizen & John Mauldin, Co-Founders, Lifespan Edge, Inc. This brief paper by Patrick Cox does the important job of summarizing thousands […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis therapeutic plasma exchange tpe
Aging Research How does Therapeutic Plasma Exchange (TPE) make you and your body and mind younger? January 4, 2025 / June 13, 2025 by Mae Savick By Dr. Mike Roizen As we stand on the cusp of revolutionary advances in medical science, the quest to understand and potentially reverse the aging process captures the imagination of researchers and the public alike. Among the promising avenues of exploration is therapeutic plasma exchange (TPE), a process that has shown intriguing potential in decreasing […] Read more antiaging Apheresis dr. dobri kiprov dr. michael roizen longevity therapeutic plasma exchange tpe
Cancer Research Revolutionizing Cancer Treatment: Plasma Exchange for Advanced Melanoma January 2, 2025 / June 13, 2025 by Mae Savick A new clinical trial, the ReCIPE-M1 study, is exploring an innovative way to treat advanced melanoma (a type of skin cancer) by combining therapeutic plasma exchange (TPE) with existing cancer immunotherapy. The goal is to improve the effectiveness of immunotherapy, which currently works for only about one-third of patients and eventually loses effectiveness for most. […] Read more melanoma ReCIPE-M1 therapeutic plasma exchange tpe
General Research What’s the Difference Between Plasma Donation and Therapeutic Plasma Exchange (TPE)? December 31, 2024 / June 13, 2025 by Mae Savick Plasma donation and TPE are completely different procedures with distinct goals and outcomes. Here’s a clear comparison: Plasma Donation: Plasma donation involves removing a small volume of plasma (typically 500–800 ml) from your body. No replacement fluid is given, as your body naturally replenishes this small loss over time. The primary purpose of plasma donation […] Read more donating plasma dr. dobri kiprov plasma therapeutic plasma exchange tpe
Aging Research How Plasma Exchange Could Help Turn Back the Clock on Aging December 18, 2024 / June 14, 2025 by Mae Savick By Dr. Dobri Kiprov Chief Medical Officer A recent study explored how a procedure called therapeutic plasma exchange (TPE) could slow down the biological aging process. TPE involves removing a person’s blood plasma and replacing it with a plasma substitute, sometimes combined with immunoglobulins (IVIG). The study showed that this procedure not only helps “reset” […] Read more dr. dobri kiprov IVIG therapeutic plasma exchange tpe
General Research Plasma exchange for Guillain-Barré syndrome November 6, 2024 / June 13, 2025 by Unmesh deolekar | Leave a Comment This systematic review examines the effectiveness of plasma exchange (PE) in treating Guillain-Barré syndrome, an acute inflammatory condition affecting peripheral nerves that often leads to paralysis. Guillain-Barré syndrome is believed to be caused by autoimmune responses, including harmful antibodies, which PE can help remove from the bloodstream. The procedure involves connecting the patient to a […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis biotech Grifols therapeutic plasma exchange tpe
Brain Health Research Neuroimaging analyses from a randomized, controlled study to evaluate plasma exchange with albumin replacement in mild‑to‑moderate Alzheimer’s disease: additional results from the AMBAR study November 6, 2024 / June 13, 2025 by Unmesh deolekar | Leave a Comment This study, part of the AMBAR phase 2b/3 clinical trial, investigated the effects of therapeutic plasma exchange (PE) with albumin replacement on brain structure and function in patients with mild-to-moderate Alzheimer’s disease (AD). Patients were divided into four groups: three received PE with varying doses of albumin (some with intravenous immunoglobulin, IVIG), while the fourth […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis biotech Grifols therapeutic plasma exchange tpe
Brain Health Research Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin November 6, 2024 / June 13, 2025 by Unmesh deolekar | Leave a Comment This phase 2b/3 trial evaluated the effects of plasma exchange (PE) with albumin replacement on patients with mild-to-moderate Alzheimer’s disease (AD). A total of 347 patients were randomized into three This study challenges the idea that young blood is necessary for tissue rejuvenation, showing instead that “neutral blood exchange” (NBE) — replacing half of an […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis biotech Grifols therapeutic plasma exchange tpe
Brain Health Research A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer’s disease: Primary results of the AMBAR Study November 6, 2024 / June 13, 2025 by Unmesh deolekar | Leave a Comment This phase 2b/3 trial evaluated the effects of plasma exchange (PE) with albumin replacement on patients with mild-to-moderate Alzheimer’s disease (AD). A total of 347 patients were randomized into three treatment groups with varying doses of albumin and intravenous immunoglobulin (IVIG) or a placebo group. The treatment included an initial 6-week period of weekly PE, […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis biotech Grifols therapeutic plasma exchange tpe
Brain Health Research Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial November 6, 2024 / June 13, 2025 by Unmesh deolekar | Leave a Comment This study examined whether plasma exchange (PE) with albumin replacement could alter amyloid-β (Aβ) levels in cerebrospinal fluid (CSF) and plasma and improve cognitive function in patients with mild-to-moderate Alzheimer’s disease (AD). In this phase II trial, 42 AD patients were assigned to either PE treatment or a control group. Treated patients received up to […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis biotech Grifols therapeutic plasma exchange tpe
Aging Research Application of biological age assessment of Chinese population in potential anti-ageing technology November 6, 2024 / June 13, 2025 by Unmesh deolekar | Leave a Comment This study aimed to create a biological age assessment formula for the Chinese population and evaluate the effectiveness of double filtration plasmapheresis as an anti-aging intervention. Researchers recruited 915 participants, analyzing 34 blood markers to identify aging biomarkers and develop a biological age formula for both males and females. Double filtration plasmapheresis was then tested […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis biotech Grifols therapeutic plasma exchange tpe
Aging Research Diluting blood plasma rejuvenates tissue, reverses aging in mice November 6, 2024 / June 13, 2025 by Unmesh deolekar | Leave a Comment UC Berkeley researchers found that diluting the blood plasma of old mice with a saline and albumin solution—without using young blood—rejuvenates tissues in the brain, liver, and muscles. This “neutral blood exchange” lowers harmful, age-associated proteins and allows beneficial proteins to rebound, providing effects similar to or better than young blood transfusions. Key findings include: […] Read more Alzheimers Disease AMBAR AMBAR Study Apheresis biotech Grifols therapeutic plasma exchange tpe
